Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717592 | 0.85 | CASP1 (0.37) | KMT2AKDM4EHTTPOLBALDH1A1 | |
| SCHEMBL2058988 | 0.84 | KMT2A (0.44) | KMT2ACD69KDM4EPKMHTT | |
| SCHEMBL2059331 | 0.76 | KMT2A (0.46) | KMT2ACD69KDM4EPKMHTT | |
| SCHEMBL4149747 | 0.75 | LMNA (0.48) | KDM4EHTTHIF1ASMN1; SMN2POLB | |
| SCHEMBL31518061 | 0.74 | MAOA (0.48) | KDM4EHIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9965997 | 0.70 | L3MBTL1 (0.56) | KDM4EALOX15PTGDR2SMN1; SMN2POLB | |
| SCHEMBL14750655 | 0.70 | CD69 (0.46) | KMT2ACD69HTTALOX15SMN1; SMN2 | |
| SCHEMBL7390249 | 0.70 | SCN5A (0.54) | KMT2ACD69HTTALOX15SMN1; SMN2 | |
| SCHEMBL5717644 | 0.70 | ALOX15 (0.41) | KMT2ACD69KDM4EPKMHTT | |
| SCHEMBL3185529 | 0.69 | MAOA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |