Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | MC1R | Q01726 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864904 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL6262503 | 0.95 | ALDH1A1 (0.49) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL30267569 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL5103764 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL6938672 | 0.84 | ALDH1A1 (0.70) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL9403533 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL12727873 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL9656371 | 0.81 | MLYCD (0.50) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL13915059 | 0.79 | S100A4 (0.45) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL10537588 | 0.79 | TRPM8 (0.49) | ALDH1A1LMNATP53SMN1; SMN2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927720-B1 | A process for making N-(4-fluorophenyl)-N-(1-methylethyl)-2-[(5-trifluoromethyl)-1,3,4-thiadiazol-2-yl)-oxy]-acetamide using an aprotic, aromatic solvent | BAYER AG (US) | 2005-11-02 | — | — | EP | claimed |
| CN-1142924-C | Process for producing thiadiazol acetamides deriv. | — | 2004-03-24 | — | — | CN | claimed |
| CN-1134424-C | Process for making thiadiazol-acetamides deriv. using aprotic, aromatic solvent | Ĭ��ר���ɷ�����˾ | 2004-01-14 | — | — | CN | claimed |
| EP-0922701-B1 | A process for producing N-(4-fluorophenyl)-N-(1-methylethyl)-2-[(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)-oxy]-acetamide | BAYER AG (US) | 2003-07-30 | — | — | EP | claimed |
| CN-1224008-A | Process for making thiadiazol-acetamides deriv. using aprotic, aromatic solvent | BAYER AG (US) | 1999-07-28 | — | — | CN | claimed |
| CN-1224007-A | Process for producing thiadiazol acetamides deriv. | BAYER AG (US) | 1999-07-28 | — | — | CN | claimed |
| EP-0927720-A1 | A process for making N-(4-fluorophenyl)-N-(1-methylethyl)-2-[(5-trifluoromethyl)-1,3,4-thiadiazol-2-yl)-oxy]-acetamide using an aprotic, aromatic solvent | Bayer Corporation (US) | 1999-07-07 | — | — | EP | claimed |
| EP-0922701-A1 | A process for producing N-(4-fluorophenyl)-N-(1-methylethyl)-2-[(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)-oxy]-acetamide | Bayer Corporation (US) | 1999-06-16 | — | — | EP | claimed |
| US-5895818-A | Process for making N-(4-fluorophenyl)-N-(1-methylethyl)-2- (5-trifuloromethyl)-1,3,4-thiadiazol-2-yl)oxy!acetamide using an aprotic, aromatic solvent | BAYER CORPORATION (US) | 1999-04-20 | — | — | US | claimed |
| US-5852202-A | Process for isolating N-(4-fluorophenyl)-N-(1-methylethyl)-2- (5-trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy!acetamide | BAYER CORPORATION (US) | 1998-12-22 | — | — | US | claimed |
| US-5808152-A | Synthesis of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide using sodium formate | BAYER CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| US-5808153-A | Conversion of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide acetate to N-4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide | BAYER CORPORATION | 1998-09-15 | — | — | US | claimed |
| US-5792872-A | REACTING 2-(METHYLSULFONYL)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE WITH N-(4-FLUOROPHENYL)-2-HYDROXY-N-(1-METHYLETHYL)ACETAMIDE IN THE PRESENCE OF AN AQUEOUS ALKALI AND APROTIC SOLVENT | BAYER CORPORATION (US) | 1998-08-11 | — | — | US | claimed |
| JP-11246539-A | — | — | None | — | — | JP | disclosed |
| JP-11240875-A | — | — | None | — | — | JP | disclosed |
| EP-4073050-A2 | NOVEL CRYSTALLINE FORMS OF FLUFENACET, METHODS FOR THEIR PREPARATION AND USE OF THE SAME | Jiangsu Rotam Chemistry Co., Ltd (CN) | 2022-10-19 | — | — | EP | disclosed |
| WO-1996017517-A1 | HYDRAULIC FLUIDS FOR USE IN AIRCRAFT | CHEVRON U.S.A. INC. (US) | 1996-06-13 | — | — | WO | disclosed |
| WO-1996008488-A1 | HERBICIDAL HETEROCYCLYL-1,2,4-OXA- OR THIA-DIAZOLYLOXYACETAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-21 | — | — | WO | disclosed |
| EP-0688763-A1 | Process for preparing anilides of hydroxycarboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-27 | — | — | EP | disclosed |
| EP-0678502-A1 | Process for preparing glycoloylanilides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-25 | — | — | EP | disclosed |