Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116753 | 0.82 | KDM4E (0.46) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL57318 | 0.79 | KDM4E (0.50) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL127151 | 0.79 | KDM4E (0.56) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL27504571 | 0.77 | PTGS1 (0.49) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| Biphenyl SCHEMBL1363812 | 0.77 | CYP2A6 (0.48) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL6252273 | 0.77 | KDM4E (0.41) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL18385057 | 0.77 | KDM4E (0.53) | KDM4ENPC1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL16189447 | 0.76 | DHODH (0.37) | KDM4ECYP2A6SMN1; SMN2LMNAHTT | |
| SCHEMBL923479 | 0.76 | PTGS1 (0.47) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 | |
| SCHEMBL17449595 | 0.76 | HTR1A (0.43) | NPY5RKDM4ENPC1CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142895-B1 | BORANE DERIVATIVES AND ORGANIC ELECTROLUMINESCENTS | CHISSO CORP (JP) | 2006-07-05 | — | — | EP | disclosed |
| EP-1113017-B1 | SILOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | CHISSO CORP (JP) | 2005-12-21 | — | — | EP | disclosed |
| US-6767654-B2 | COMPOUNDS WHICH INTRAMOLECULARLY CONTAIN BORON ATOMS HAVE UNIQUE OPTIC AND ELECTRONIC PROPERTIES PROBABLY OWING TO THE EXISTENCE OF THE EMPTY P ORBITAL OF THE BORON ATOM | CHISSO CORPORATION (JP) | 2004-07-27 | — | — | US | disclosed |
| US-20030152800-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | JNC CORPORATION (JP) | 2003-08-14 | — | — | US | disclosed |
| US-6376694-B1 | Silole derivatives and organic electroluminescent element containing the same | CHISSO CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1142895-A1 | BORANE DERIVATIVES AND ORGANIC ELECTROLUMINESCENTS | CHISSO CORPORATION (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-1113017-A1 | SILOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | CHISSO CORPORATION (JP) | 2001-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030152800-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | LEF1, ZYX, ELP1 | NPY5R 720/4885KDM4E 1330/4885NPC1 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.