Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712496 | 0.86 | LMNA (0.58) | LMNASMN1; SMN2IDO1TAAR1TSHR | |
| SCHEMBL9206248 | 0.86 | CXCL8 (0.47) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL6618219 | 0.83 | LMNA (0.59) | LMNASMN1; SMN2IDO1TAAR1TSHR | |
| SCHEMBL5787969 | 0.83 | IDO1 (0.56) | LMNASMN1; SMN2IDO1TAAR1CYP3A4 | |
| SCHEMBL12227221 | 0.82 | L3MBTL1 (0.50) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL12227220 | 0.82 | L3MBTL1 (0.49) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL7993174 | 0.81 | L3MBTL1 (0.53) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6015464 | 0.80 | MEN1 (0.40) | TSHRCYP2D6MAPTMEN1KMT2A | |
| SCHEMBL29737506 | 0.80 | L3MBTL1 (0.64) | LMNASMN1; SMN2IDO1TAAR1TSHR | |
| SCHEMBL266821 | 0.80 | L3MBTL1 (0.64) | LMNASMN1; SMN2IDO1TAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | disclosed |
| EP-1408986-A4 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1408986-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | disclosed |