Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227220 | 0.87 | L3MBTL1 (0.49) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL12227221 | 0.87 | L3MBTL1 (0.50) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL6617057 | 0.85 | L3MBTL1 (0.56) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL5783356 | 0.84 | MEN1 (0.41) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL9206248 | 0.82 | CXCL8 (0.47) | L3MBTL1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23478172 | 0.81 | L3MBTL1 (0.70) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL31274509 | 0.81 | L3MBTL1 (0.70) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL5719348 | 0.81 | LMNA (0.56) | MAPTALDH1A1MEN1GAAKMT2A | |
| SCHEMBL8260843 | 0.81 | L3MBTL1 (0.49) | L3MBTL1MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL28640918 | 0.81 | ALDH1A1 (0.51) | L3MBTL1MAPTALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099582-A2 | COMPOSITIONS AND METHODS FOR TREATING DIABETES USING LISOFYLLINE ANALOGS AND ISLET NEOGENESIS ASSOCIATED PEPTIDE | DIAKINE THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |