Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719618 | 1.00 | ITGA4 (0.48) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL7378303 | 0.91 | ITGA4 (0.45) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL9842191 | 0.91 | ITGA4 (0.45) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL5719575 | 0.87 | ITGA4 (0.55) | ITGA4ITGB1LTA4H | |
| SCHEMBL6561273 | 0.87 | ITGA4 (0.55) | ITGA4ITGB1LTA4H | |
| SCHEMBL10883352 | 0.86 | ITGA4 (0.44) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL5719932 | 0.86 | ITGA4 (0.50) | ITGA4ITGB1LTA4HSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6509920 | 0.86 | ITGA4 (0.54) | ITGA4ITGB1LTA4H | |
| SCHEMBL5719938 | 0.86 | ITGA4 (0.50) | ITGA4ITGB1LTA4HSMN1; SMN2 | |
| SCHEMBL7338844 | 0.83 | LTA4H (0.65) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668007-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026163-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-24 | — | — | WO | disclosed |