Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842191 | 1.00 | ITGA4 (0.45) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL5719732 | 0.91 | ITGA4 (0.48) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL5719618 | 0.91 | ITGA4 (0.48) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL7991533 | 0.84 | LTA4H (0.55) | LTA4H | |
| SCHEMBL4747567 | 0.84 | ITGA4 (0.47) | ITGA4ITGB1 | |
| SCHEMBL6561273 | 0.83 | ITGA4 (0.55) | ITGA4ITGB1LTA4H | |
| SCHEMBL5719575 | 0.83 | ITGA4 (0.55) | ITGA4ITGB1LTA4H | |
| SCHEMBL10883352 | 0.82 | ITGA4 (0.44) | ITGA4ITGB1LTA4HMEN1ALDH1A1 | |
| SCHEMBL5719938 | 0.82 | ITGA4 (0.50) | ITGA4ITGB1LTA4H | |
| Hydrochloric Acid SCHEMBL6509920 | 0.82 | ITGA4 (0.54) | ITGA4ITGB1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4534897-A | Piperazinone, piperazine, 1,4-diazepin-2-one and 1,4-diazepine intermediate compounds | THE UPJOHN COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| US-4338305-A | LUTEINIZING HORMONE RELEASING HORMONE; CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4272432-A | Claudogenic-interceptive nonapeptide | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-3992530-A | [D-2-(1,4-Cyclohexadienyl)gly]6 -des-gly10 -lrh nonapeptide amides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3988308-A | (Tyr3, Tyr14)-SRIF and intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |