Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720638 | 1.00 | MMP2 (0.41) | MMP2MMP9ACEKMT2AANPEP | |
| SCHEMBL9856555 | 0.85 | MMP2 (0.50) | MMP2MMP9ACEKMT2AITGB3 | |
| SCHEMBL9856540 | 0.85 | MMP2 (0.50) | MMP2MMP9ACEKMT2AITGB3 | |
| SCHEMBL5720686 | 0.83 | ACE (0.52) | MMP2MMP9ACEANPEPCPB2 | |
| SCHEMBL5720685 | 0.83 | ACE (0.52) | MMP2MMP9ACEANPEPCPB2 | |
| SCHEMBL28836164 | 0.72 | ACE (0.48) | ACEITGB3ITGA2BCASP1ECE1 | |
| SCHEMBL28836162 | 0.71 | ITGB3 (0.50) | ITGB3ITGA2BCASP1ECE1 | |
| SCHEMBL28836163 | 0.71 | ITGB3 (0.50) | ITGB3ITGA2BCASP1ECE1 | |
| SCHEMBL13750377 | 0.71 | MMP2 (0.51) | MMP2MMP9KMT2AITGB3ITGA2B | |
| SCHEMBL287192 | 0.71 | FOLH1 (0.50) | CPB2CASP1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513868-B1 | PROCESS FOR THE PRODUCTION OF LISINOPRIL | EOS ECZACIBASI OZGUN KIMYASAL (TR) | 2006-08-09 | — | — | EP | claimed |