Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856540 | 1.00 | MMP2 (0.50) | MMP2MMP9TSHRACEMAPT | |
| SCHEMBL5720645 | 0.85 | MMP2 (0.41) | MMP2MMP9TSHRACEMAPT | |
| SCHEMBL5720638 | 0.85 | MMP2 (0.41) | MMP2MMP9TSHRACEMAPT | |
| SCHEMBL13750377 | 0.81 | MMP2 (0.51) | MMP2MMP9MAPTKDM4EMAPK1 | |
| SCHEMBL661267 | 0.79 | ACE (0.65) | MMP2MMP9ACETLR2ITGB3 | |
| SCHEMBL7267746 | 0.79 | ACE (0.65) | MMP2MMP9ACETLR2ITGB3 | |
| SCHEMBL5870137 | 0.79 | ACE (0.65) | MMP2MMP9ACETLR2ITGB3 | |
| SCHEMBL29017599 | 0.78 | MMP2 (0.53) | MMP2MMP9ACEFOLH1TLR2 | |
| SCHEMBL607886 | 0.78 | ITGB3 (0.60) | MMP2MMP9FOLH1ITGB3ITGA2B | |
| SCHEMBL607885 | 0.78 | ITGB3 (0.60) | MMP2MMP9FOLH1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239062-B1 | N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |