Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | CPA2 | P48052 | 1/20 | 0.41 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720685 | 1.00 | ACE (0.52) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL6237696 | 0.86 | ACE (0.58) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL6240311 | 0.86 | ACE (0.58) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL27458051 | 0.86 | ACE (0.58) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL7267746 | 0.86 | ACE (0.65) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL5870137 | 0.86 | ACE (0.65) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL661267 | 0.86 | ACE (0.65) | ACEMMEANPEPLNPEPERAP2 | |
| SCHEMBL5720638 | 0.83 | MMP2 (0.41) | ACEANPEPCASP1MMP2MMP9 | |
| SCHEMBL5720645 | 0.83 | MMP2 (0.41) | ACEANPEPCASP1MMP2MMP9 | |
| SCHEMBL5720692 | 0.82 | ACE (0.40) | ACEANPEPLNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513868-B1 | PROCESS FOR THE PRODUCTION OF LISINOPRIL | EOS ECZACIBASI OZGUN KIMYASAL (TR) | 2006-08-09 | — | — | EP | claimed |