Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122814 | 0.76 | GPR132 (0.53) | HRH3SLC6A5 | |
| SCHEMBL1122690 | 0.76 | GPR132 (0.53) | HRH3SLC6A5 | |
| SCHEMBL5720786 | 0.75 | BDKRB2 (0.52) | HRH3SLC6A5SENP8SENP7SENP6 | |
| SCHEMBL1123143 | 0.73 | RXRA (0.72) | HRH3NR4A2RXRARXRBNPC1 | |
| SCHEMBL1122538 | 0.73 | BDKRB2 (0.50) | HRH3RAB9APLK1 | |
| SCHEMBL1123094 | 0.71 | NPC1 (0.70) | HRH3RXRARXRBMEN1NPC1 | |
| SCHEMBL7738901 | 0.71 | MAOB (0.68) | HRH3RXRARXRBNPC1RAB9A | |
| SCHEMBL10789890 | 0.70 | RXRA (0.70) | NR4A2RXRARXRBMEN1NPC1 | |
| SCHEMBL1123135 | 0.69 | GPR132 (0.54) | NPC1RAB9A | |
| SCHEMBL24534839 | 0.69 | PLK1 (0.59) | MEN1NPC1RAB9AKMT2APLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | claimed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | claimed |