Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138970 | 0.89 | CDK2 (0.78) | TTRCDK2CA2CA1CA9 | |
| SCHEMBL108422 | 0.87 | LDHA (0.64) | TTRCDK2CA2CA1CA9 | |
| SCHEMBL9669785 | 0.82 | CDK2 (0.58) | TTRCDK2CA2CA1CA9 | |
| SCHEMBL29518656 | 0.81 | TTR (1.00) | TTRCDK2NSD2ALDH1A1CYP3A4 | |
| SCHEMBL9927438 | 0.81 | TTR (0.66) | TTRCA2NSD2ALDH1A1CYP3A4 | |
| SCHEMBL147103 | 0.81 | TTR (1.00) | TTRCDK2NSD2ALDH1A1CYP3A4 | |
| SCHEMBL30804445 | 0.81 | TTR (1.00) | TTRCDK2NSD2ALDH1A1CYP3A4 | |
| SCHEMBL8516378 | 0.81 | TTR (0.66) | TTRCA2CA1CA9CA12 | |
| Hydrochloric Acid SCHEMBL9670851 | 0.80 | CDK2 (0.56) | TTRCDK2CA2CA1CA9 | |
| SCHEMBL2951284 | 0.79 | TTR (0.96) | TTRCDK2NSD2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994385-B1 | CHANGED CONDITION INDICATOR | COOPERMAN ISADORE (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-1709128-B1 | FLOOR FINISH COMPOSITION, LAMINATES, AND METHODES FOR TREATING FLOORS | ECOLAB INC (US) | 2017-10-04 | — | — | EP | disclosed |
| US-9199959-B2 | HIV replication inhibitor | SHIONOGI & CO., LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8044101-B2 | Nitrosation-inducible inhibitors biological macromolecules | NEW YORK UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-7994251-B2 | System for coating floors | ECOLAB USA INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| US-7770534-B2 | Changed condition indicator | THERMOPROX | 2010-08-10 | — | — | US | disclosed |
| US-7612085-B2 | Sigma 2 receptor ligands and therapeutic uses therefor | WASHINGTON UNIVERSITY (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NEW YORK UNIVERSITY (US) | 2009-07-23 | — | — | US | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0283959-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-02 | — | — | EP | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4912108-A | Containing hydroxy substitution | A/S FERROSAN (DK) | 1990-03-27 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | disclosed |
| EP-0283959-A1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-28 | — | — | EP | disclosed |
| US-4022799-A | DYEING, PRINTING OF NATURAL AND SYNTHETIC MATERIALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-4001253-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | TTR 594/4885CDK2 652/4885CA2 1279/4885 |
| US-20090186829-A1 | Nitrosation-Inducible Inhibitors Biological Macromolecules | NOS2, NOS1, NOS3 | TTR 790/4885CDK2 939/4885CA2 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.