Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105979 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GRM8GRM6GRM4TDP1 | |
| SCHEMBL2452348 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GRM8GRM6GRM4TDP1 | |
| SCHEMBL6474872 | 0.84 | KMT2A (0.56) | ALDH1A1TDP1KMT2AMEN1NPC1 | |
| SCHEMBL1857061 | 0.82 | FNTA (0.58) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL3859569 | 0.81 | KMO (0.55) | GRM8GRM6GRM4KMT2AMEN1 | |
| SCHEMBL666885 | 0.81 | KMO (0.55) | GRM8GRM6GRM4KMT2AMEN1 | |
| SCHEMBL19833069 | 0.81 | NPC1 (0.48) | ALDH1A1GRM8GRM6GRM4TDP1 | |
| SCHEMBL4833185 | 0.81 | NPC1 (0.48) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL18133735 | 0.81 | NPC1 (0.48) | ALDH1A1GRM8GRM6GRM4TDP1 | |
| SCHEMBL3310878 | 0.81 | KMO (0.55) | GRM8GRM6GRM4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | UBE INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| CN-1245519-C | Enzymatic process for the enantiomeric resolution of amino acids | AVENTIS PHARMA SA (FR) | 2006-03-15 | — | — | CN | disclosed |
| EP-1621529-A1 | 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO | Ube Industries, Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-6902927-B2 | Enzymatic process for the enantiomeric resolution of amino acids | AVENTIS PHARMA S.A. (FR) | 2005-06-07 | — | — | US | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| CN-1551922-A | Enzymatic process for the enantiomeric resolution of amino acids | �㶫��������ҽҩ�ɷ�����˾ | 2004-12-01 | — | — | CN | disclosed |
| US-20030087399-A1 | Enzymatic process for the enantiomeric resolution of amino acids | AVENTIS PHARMA S.A. (FR) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | ALAD, ARSA, ALDH7A1 | ALDH1A1 258/4885GRM8 4544/4885GRM6 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.