Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720856 | 0.91 | MEN1 (0.40) | SLC2A1SMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL2367085 | 0.89 | SMN1; SMN2 (0.39) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720898 | 0.87 | SMN1; SMN2 (0.45) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720925 | 0.86 | FAAH (0.47) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720835 | 0.86 | L3MBTL1 (0.48) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720923 | 0.86 | SLC2A1 (0.43) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720899 | 0.86 | FAAH (0.48) | SLC2A1SMN1; SMN2L3MBTL1NPC1HPGD | |
| SCHEMBL5720836 | 0.85 | TSHR (0.49) | SLC2A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL5697642 | 0.85 | TSHR (0.49) | SLC2A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL5720859 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867207-A1 | PHENOXYETHYL PIPERIDINE COMPOUNDS | Eli Lilly and Company (US) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014004229-A1 | PHENOXYETHYL PIPERIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-01-03 | — | — | WO | disclosed |
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | UBE INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1621529-A1 | 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO | Ube Industries, Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | ALAD, ARSA, ALDH7A1 | SLC2A1 3606/4885SMN1; SMN2 3856/4885L3MBTL1 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.