Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721193 | 0.87 | NPC1 (0.37) | ALDH1A1HPGDCYP2A6PTGS2 | |
| SCHEMBL5721311 | 0.85 | CYP2A6 (0.33) | ALDH1A1HSD17B10CYP2A6PTGS2 | |
| SCHEMBL5721244 | 0.84 | DPP4 (0.33) | — | |
| SCHEMBL5721749 | 0.84 | CA12 (0.35) | — | |
| SCHEMBL5721844 | 0.82 | CA12 (0.31) | — | |
| SCHEMBL5721731 | 0.82 | ALDH1A1 (0.30) | ALDH1A1MAPK1 | |
| SCHEMBL5721411 | 0.82 | PTGS2 (0.32) | HDAC4HDAC2HDAC8HDAC6PTGS2 | |
| SCHEMBL5721604 | 0.81 | PTGS2 (0.33) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL5721381 | 0.80 | METAP2 (0.33) | — | |
| SCHEMBL5721706 | 0.79 | ADRB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-B1 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEM PATENTS INC (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |