Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721805 | 0.89 | RXRB (0.32) | RXRARXRB | |
| SCHEMBL5721614 | 0.89 | IKBKB (0.34) | IKBKBRXRARXRBRXRGTACR1 | |
| SCHEMBL5721657 | 0.86 | IKBKB (0.32) | IKBKBCNR1CNR2 | |
| SCHEMBL5721387 | 0.84 | IKBKB (0.40) | IKBKBRXRARXRBRXRGCNR1 | |
| SCHEMBL5721448 | 0.84 | IKBKB (0.31) | IKBKB | |
| SCHEMBL5721651 | 0.83 | RXRA (0.35) | IKBKBRXRARXRBRXRGTACR1 | |
| SCHEMBL5721450 | 0.82 | TACR1 (0.36) | TACR1CNR1CNR2 | |
| SCHEMBL5721474 | 0.82 | IKBKB (0.35) | IKBKBRXRARXRBRXRGS1PR1 | |
| SCHEMBL5721595 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL5721263 | 0.81 | CTSS (0.33) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |