Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721818 | 0.90 | HEXA (0.33) | NPC1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL5721706 | 0.90 | ADRB2 (0.31) | — | |
| SCHEMBL5721687 | 0.84 | HEXA (0.32) | — | |
| SCHEMBL5721551 | 0.83 | HEXA (0.31) | — | |
| SCHEMBL5721762 | 0.82 | MAPT (0.30) | MAPT | |
| SCHEMBL5721193 | 0.81 | NPC1 (0.37) | NPC1ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL5721325 | 0.79 | PDCD1 (0.33) | MAPT | |
| SCHEMBL5721234 | 0.79 | TRPA1 (0.33) | — | |
| SCHEMBL5721411 | 0.79 | PTGS2 (0.32) | — | |
| SCHEMBL5721563 | 0.77 | METAP2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |