Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721762 | 0.90 | MAPT (0.30) | MAPT | |
| SCHEMBL5721760 | 0.82 | CNR1 (0.37) | TP53MAPT | |
| SCHEMBL5721381 | 0.82 | METAP2 (0.33) | — | |
| SCHEMBL5721400 | 0.81 | HEXA (0.33) | — | |
| SCHEMBL5721818 | 0.81 | HEXA (0.33) | KDM4ETP53L3MBTL1 | |
| SCHEMBL5721411 | 0.81 | PTGS2 (0.32) | — | |
| SCHEMBL5721234 | 0.81 | TRPA1 (0.33) | — | |
| SCHEMBL5721826 | 0.76 | PDCD1 (0.33) | TP53L3MBTL1 | |
| SCHEMBL5721244 | 0.74 | DPP4 (0.33) | — | |
| SCHEMBL5721691 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |