SCHEMBL572347

SCHEMBL572347

CCOC(=O)c1ccc(N)c(C(O)CC)c1C(O)CC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.51
HSD17B10 Q99714 3/20 0.51
TSHR P16473 1/20 0.46
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAOA P21397 1/20 0.42
CDC25B P30305 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 6/20 0.40
GAA P10253 4/20 0.40
HPGD P15428 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066277 0.81 GABRP (0.40) ALDH1A1HSD17B10LMNACYP1A2CYP3A4
SCHEMBL4075240 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL28004805 0.78 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL55681 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL5946756 0.73 ALDH1A1 (0.65) ALDH1A1HSD17B10TSHRCDC25BKMT2A
SCHEMBL27883893 0.72 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL625558 0.72 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL6858202 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL11429762 0.71 ALDH1A1 (0.57) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL27556629 0.71 ALDH1A1 (0.57) ALDH1A1HSD17B10TSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230034183-A1 AQUEOUS SUNCARE FORMULATION DOW GLOBAL TECHNOLOGIES LLC 2023-02-02 US claimed
EP-3307395-B1 SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS ISP INVESTMENTS LLC (US) 2020-08-05 EP claimed
US-10351523-B2 UV-absorbing compounds with at least one reactive hydrogen ISP INVESTMENTS LLC 2019-07-16 US claimed
US-10328003-B2 Solubilizing agents for active or functional organic compounds ISP INVESTMENTS LLC (US) 2019-06-25 US claimed
US-20180168970-A1 SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS ISP INVESTMENTS LLC (US) 2018-06-21 US claimed
EP-3307395-A1 SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS ISP Investments LLC (US) 2018-04-18 EP claimed
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS LLC (US) 2018-04-12 US claimed
WO-2016201260-A1 SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS ISP INVESTMENTS INC. (US) 2016-12-15 WO claimed
WO-2014149363-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS INC. (US) 2014-09-25 WO claimed
US-20130236404-A2 SUBSTANCES AND COMPOSITIONS FOR ENHANCING DNA REPAIR AND METHODS OF USE CORNELL UNIVERSITY (US) 2013-09-12 US claimed
EP-2451534-A2 COSMETIC COMPOSITIONS AND METHODS FOR ENHANCED UV PROTECTION U.S. Cosmetics Corporation (US) 2012-05-16 EP claimed
WO-2010148180-A2 COSMETIC COMPOSITIONS AND METHODS FOR ENHANCED UV PROTECTION U.S. COSMETICS CORPORATION (US) 2010-12-23 WO claimed
EP-1092421-B1 Method for preparing ultraviolet radiation absorbing compositions ROHM & HAAS (US) 2007-03-21 EP claimed
EP-1490018-A2 SUNSCREEN COMPOSITIONS AND METHODS AND MATERIALS FOR PRODUCING THE SAME The C.P. Hall Company (US) 2004-12-29 EP claimed
WO-2003075877-A2 SUNSCREEN COMPOSITIONS AS WELL AS METHODS AND MATERIALS FOR PRODUCING THE SAME, WHEREIN THE PHOTODECAY RATE OF THE FILTER SYSTEM IS REDUCED BY CONTROLLING THE POLARITY OF THE SOLVENT SYSTEM THE C.P. HALL COMPANY (US) 2003-09-18 WO claimed
US-6485713-B1 CONTROLLING THE POLARITY OF A SOLVENT SYSTEM IN THE COMPOSITION TO CONTROL THE RATE OF PHOTODECAY OF A FILTER SYSTEM IN THE COMPOSITION THE C. P. HALL COMPANY 2002-11-26 US claimed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US claimed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP claimed
US-4731242-A Waterproof sunscreen compositions PALINCZAR VICTOR (US) 1988-03-15 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10328003-B2 Solubilizing agents for active or functional organic compounds C1S, POLR1C, TYR ALDH1A1 1257/4885HSD17B10 1208/4885TSHR 2006/4885
US-20180168970-A1 SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS C1S, POLR1C, TYR ALDH1A1 1257/4885HSD17B10 1208/4885TSHR 2006/4885
US-10351523-B2 UV-absorbing compounds with at least one reactive hydrogen ERCC1, ERCC4, UNG ALDH1A1 263/4885HSD17B10 2419/4885TSHR 4000/4885
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ERCC1, ERCC4, UNG ALDH1A1 263/4885HSD17B10 2419/4885TSHR 4000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.