SCHEMBL625558

SCHEMBL625558

CCOC(=O)c1cccc(C(O)CC)c1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
HSD17B10 Q99714 4/20 0.54
TSHR P16473 2/20 0.53
CDC25B P30305 4/20 0.47
MAPT P10636 4/20 0.44
KMT2A Q03164 4/20 0.44
RAB9A P51151 4/20 0.44
ALOX15 P16050 3/20 0.44
CYP1A2 P05177 3/20 0.44
MEN1 O00255 3/20 0.44
GAA P10253 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
HPGD P15428 3/20 0.44
CYP3A4 P08684 2/20 0.44
USP2 O75604 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAPK10 P53779 1/20 0.44
PTK2B Q14289 1/20 0.44
NCOA1 Q15788 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16973272 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10TSHRCDC25BKMT2A
SCHEMBL27424975 0.82 TSHR (0.70) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL17910041 0.81 G6PD (0.49) ALDH1A1HSD17B10MAPTKMT2AALOX15
SCHEMBL4075240 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL27508673 0.78 ALDH1A1 (0.60) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL5808886 0.78 ALDH1A1 (0.64) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL2925689 0.78 ALDH1A1 (0.74) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL23294932 0.77 ALDH1A1 (0.58) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL31091521 0.76 CA12 (0.62) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL3458043 0.76 ALDH1A1 (0.62) ALDH1A1HSD17B10TSHRCDC25BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018143-A2 WATER-DISPERSIBLE PATCH CONTAINING AN ACTIVE AGENT FOR DERMAL DELIVERY Eastman Chemical Company (US) 2009-01-28 EP claimed
WO-2007133509-A2 WATER-DISPERSIBLE PATCH CONTAINING AN ACTIVE AGENT FOR DERMAL DELIVERY EASTMAN CHEMICAL COMPANY (US) 2007-11-22 WO claimed
US-20070259029-A1 Water-dispersible patch containing an active agent for dermal delivery EASTMAN CHEMICAL COMPANY 2007-11-08 US claimed
EP-4398863-A1 THERMO-SENSITIVE COMPOSITION AND METHOD FOR PREPARATION THEREOF BASF SE (DE) 2024-07-17 EP disclosed
EP-3439625-B1 PERSONAL CARE COMPOSITIONS AND METHODS FOR USING SUCH COMPOSITIONS SPECIALTY OPERATIONS FRANCE (FR) 2024-07-17 EP disclosed
US-12023401-B2 Sulfate-free personal care compositions and methods for using such compositions SPECIALITY OPERATIONS FRANCE (FR) 2024-07-02 US disclosed
WO-2024100162-A1 PROCESS FOR FORMING AN AQUEOUS DISPERSION OF COPOLYMERS, AN ADHESIVE COMPOSITION INCLUDING SUCH COPOLYMERS, A FILM OR AN ARTICLE COMPRISING THE SAME, AND A METHOD OF COATING A SUBSTRATE WACKER CHEMIE AG (DE) 2024-05-16 WO disclosed
EP-4366687-A1 THICKENING AGENT FOR PERSONAL CARE CLEANSING COMPOSITIONS BASF SE (DE) 2024-05-15 EP disclosed
US-11951201-B2 Personal care compositions and methods for using such compositions SPECIALTY OPERATIONS FRANCE (FR) 2024-04-09 US disclosed
US-20240050352-A1 RECOMBINANT SILK COMPOSITIONS AND METHODS OF MAKING THEREOF BOLT THREADS, INC. 2024-02-15 US disclosed
EP-3091969-B1 PROCESS FOR FORMING A SHAPED FILM PRODUCT JOHNSON & JOHNSON CONSUMER INC (US) 2024-01-24 EP disclosed
EP-1125540-A1 Textured film devices Johnson & Johnson Consumer Companies, Inc. (US) 2001-08-22 EP disclosed
EP-1125541-A1 Dispensing article Johnson & Johnson Consumer Companies, Inc. (US) 2001-08-22 EP disclosed
CN-1303263-A Topital delivery system for active agents JOHNSON & JOHNSON CONSUMER (US) 2001-07-11 CN disclosed
EP-1104280-A2 TOPICAL DELIVERY SYSTEMS FOR ACTIVE AGENTS Johnson & Johnson Consumer Companies, Inc. (US) 2001-06-06 EP disclosed
WO-2001001949-A9 CLEANSING COMPOSITIONS JOHNSON & JOHNSON CONSUMER (US) 2001-03-22 WO disclosed
EP-1080714-A2 Detergent compositions with enhanced depositing, conditioning and softness capabilities Johnson & Johnson Consumer Companies, Inc. (US) 2001-03-07 EP disclosed
EP-1066827-A2 Foaming oil gel compositions Johnson & Johnson Consumer Companies, Inc. (US) 2001-01-10 EP disclosed
EP-1060732-A2 Novel topical formulations comprising vesicle delivery systems JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 2000-12-20 EP disclosed
WO-2000007627-A2 TOPICAL DELIVERY SYSTEMS FOR ACTIVE AGENTS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2000-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023401-B2 Sulfate-free personal care compositions and methods for using such compositions SMURF1, KRT18, DSG1 ALDH1A1 3342/4885HSD17B10 1155/4885TSHR 4074/4885
US-11951201-B2 Personal care compositions and methods for using such compositions DSG1, SMURF1, POLR1C ALDH1A1 3653/4885HSD17B10 1357/4885TSHR 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.