Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364655 | 0.84 | — | — | |
| SCHEMBL108941 | 0.77 | CES1 (0.39) | CES2FDPSCES1CYP4F2CYP4A11 | |
| SCHEMBL249872 | 0.77 | ACLY (0.56) | ALDH1A1ACLYAKR1B1ACACBACACA | |
| SCHEMBL1327457 | 0.77 | FDPS (0.43) | CES2FDPSCES1CYP4F2CYP4A11 | |
| SCHEMBL2342593 | 0.77 | FDPS (0.38) | CES2FDPSCES1CYP4F2CYP4A11 | |
| SCHEMBL11390055 | 0.76 | CES2 (0.45) | CES2FDPSCES1 | |
| SCHEMBL6521284 | 0.75 | ACLY (0.54) | ACLYAKR1B1ACACBACACA | |
| SCHEMBL4540511 | 0.75 | ACLY (0.54) | ACLYAKR1B1ACACBACACA | |
| SCHEMBL22396506 | 0.75 | ACLY (0.54) | ACLYAKR1B1ACACBACACA | |
| Hydrochloric Acid SCHEMBL5669467 | 0.75 | ACLY (0.54) | ACLYAKR1B1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556347-A4 | GAMMA LACTAMS AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS (AN) | 2006-08-09 | — | — | EP | disclosed |
| EP-1556347-A2 | GAMMA LACTAMS AS PROSTAGLANDIN AGONISTS AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2005-07-27 | — | — | EP | disclosed |
| WO-2003103604-A2 | GAMMA LACTAMS AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V (AN) | 2003-12-18 | — | — | WO | disclosed |
| EP-0140307-A2 | 7-Oxabicycloheptane ethers | E.R. Squibb & Sons, Inc. (US) | 1985-05-08 | — | — | EP | disclosed |