Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11588216 | 0.80 | CA12 (0.53) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL13816964 | 0.78 | CYP1A2 (0.54) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL16155868 | 0.77 | CYP3A4 (0.54) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL6529545 | 0.77 | LMNA (0.60) | KMT2AMEN1LMNASETDB1GAA | |
| SCHEMBL4066478 | 0.77 | L3MBTL1 (0.48) | L3MBTL1KMT2AHPGDCA1CA2 | |
| SCHEMBL5212277 | 0.76 | TTR (0.58) | KMT2AMEN1HPGDLMNAGAA | |
| SCHEMBL5724270 | 0.76 | SETDB1 (0.57) | L3MBTL1KMT2AMEN1HPGDCA12 | |
| SCHEMBL5724700 | 0.76 | P2RX7 (0.43) | L3MBTL1HPGDLMNAPOLBSETDB1 | |
| SCHEMBL13888086 | 0.75 | HSD17B10 (0.56) | KMT2AMEN1HPGDCA12CA1 | |
| SCHEMBL2454738 | 0.75 | KMT2A (0.49) | KMT2AMEN1HPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633715-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108676-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |