SCHEMBL57243

SCHEMBL57243

O=C(Oc1ccccc1F)Oc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.49
ALDH1A1 P00352 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 1/20 0.49
PARP10 Q53GL7 1/20 0.47
CXCL8 P10145 1/20 0.47
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
KMT2A Q03164 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 1/20 0.42
NPC1 O15118 1/20 0.42
ALOX15 P16050 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29585912 1.00 FAAH (0.49) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL8499008 0.90 FAAH (0.54) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL11602464 0.88 FAAH (0.42) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL15454164 0.87 HPGD (0.59) FAAHALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL26622209 0.87 FAAH (0.44) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL18697277 0.86 FAAH (0.49) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL2940941 0.86 FAAH (0.49) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL17720770 0.85 FABP3 (0.48) FAAHALDH1A1SMN1; SMN2MAPTCXCL8
SCHEMBL57244 0.84 FAAH (0.51) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL6966435 0.84 FAAH (0.47) FAAHALDH1A1SMN1; SMN2MAPTPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255960-B1 PROCESS FOR THE PREPARATION OF A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE COVESTRO DEUTSCHLAND AG (DE) 2025-10-08 EP claimed
EP-4255960-A1 PROCESS FOR PREPARING A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE Covestro Deutschland AG (DE) 2023-10-11 EP claimed
WO-2023179324-A1 ELECTROLYTIC SOLUTION CONTAINING FLUOROBENZENE CARBONATE, AND BATTERY COMPOSED OF ELECTROLYTIC SOLUTION 香河昆仑新能源材料股份有限公司 2023-09-28 WO claimed
EP-4227293-A2 CRYSTALLINE FORMS OF 1-(ACYLOXY)-ALKYL CARBAMATE DRUG CONJUGATES OF NAPROXEN AND PREGABALIN Xgene Pharmaceutical Inc (KY) 2023-08-16 EP claimed
CN-116507663-A Method for producing polycarbonates using halogenated diaryl carbonates 科思创德国股份有限公司 2023-07-28 CN claimed
WO-2022117472-A1 PROCESS FOR PREPARING A POLYCARBONATE USING A HALOGENATED DIARYL CARBONATE COVESTRO DEUTSCHLAND AG (DE) 2022-06-09 WO claimed
EP-2951299-A1 CYSTATHIONINE BETA-SYNTHASE ENZYME FOR TREATMENT OF HOMOCYSTINURIA The Regents of The University of Colorado, A Body Corporate (US) 2015-12-09 EP claimed
WO-2014120770-A1 CYSTATHIONINE BETA-SYNTHASE ENZYME FOR TREATMENT OF HOMOCYSTINURIA THE REGENTS OF UNIVERSITY OF COLORADO (US) 2014-08-07 WO claimed
EP-1572728-B1 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF MOUNTAIN VIEW PHARMACEUTICALS (US) 2014-06-25 EP claimed
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2012-05-10 US claimed
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 WO claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US claimed
US-6569985-B2 Multistage; oligomerization using tetraalykyphosphorium catalyst and Group 1a hydroxide catalyst GENERAL ELECTRIC COMPANY 2003-05-27 US claimed
US-20030065129-A1 Method for making polycarbonate GENERAL ELECTRIC COMPANY 2003-04-03 US claimed
WO-2003014188-A1 METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-20 WO claimed
US-20030012777-A1 Polymer conjugates of proteinases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2003-01-16 US claimed
WO-2003002716-A2 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2003-01-09 WO claimed
US-6399739-B1 PROCESS CONTROL USING COMPUTERS GENERAL ELECTRIC COMPANY 2002-06-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A FAAH 1966/4885ALDH1A1 3287/4885SMN1; SMN2 3522/4885
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A FAAH 1966/4885ALDH1A1 3287/4885SMN1; SMN2 3522/4885
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof CD14, HLA-C, HLA-A FAAH 1966/4885ALDH1A1 3287/4885SMN1; SMN2 3522/4885
US-20030012777-A1 Polymer conjugates of proteinases PRNP, PRSS3, PRSS1 FAAH 3421/4885ALDH1A1 2442/4885SMN1; SMN2 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.