SCHEMBL57244

SCHEMBL57244

O=C(O)Oc1ccccc1F

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.51
CXCL8 P10145 1/20 0.50
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
PARP10 Q53GL7 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 2/20 0.43
GAA P10253 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 1/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2940941 0.84 FAAH (0.49) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL18697277 0.84 FAAH (0.49) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL57243 0.84 FAAH (0.49) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL29585912 0.84 FAAH (0.49) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL143632 0.83 KDM4E (0.46) ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL6966435 0.82 FAAH (0.47) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL1323923 0.81 KMT2A (0.63) FAAHSMN1; SMN2MAPTPARP10MRGPRX4
SCHEMBL2322496 0.80 PARP10 (0.53) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL247351 0.80 PTGS2 (0.57) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT
SCHEMBL1977066 0.80 ALDH1A1 (0.48) FAAHCXCL8ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023179324-A1 ELECTROLYTIC SOLUTION CONTAINING FLUOROBENZENE CARBONATE, AND BATTERY COMPOSED OF ELECTROLYTIC SOLUTION 香河昆仑新能源材料股份有限公司 2023-09-28 WO claimed
EP-4227293-A2 CRYSTALLINE FORMS OF 1-(ACYLOXY)-ALKYL CARBAMATE DRUG CONJUGATES OF NAPROXEN AND PREGABALIN Xgene Pharmaceutical Inc (KY) 2023-08-16 EP claimed
EP-2951299-A1 CYSTATHIONINE BETA-SYNTHASE ENZYME FOR TREATMENT OF HOMOCYSTINURIA The Regents of The University of Colorado, A Body Corporate (US) 2015-12-09 EP claimed
EP-2154138-B1 NOVEL COMPOUNDS FOR TREATMENT OF PSYCHOTIC DISORDERS, PREPARATION METHODS AND USES THEREOF LI YOUXIN (CN) 2015-08-19 EP claimed
WO-2014120770-A1 CYSTATHIONINE BETA-SYNTHASE ENZYME FOR TREATMENT OF HOMOCYSTINURIA THE REGENTS OF UNIVERSITY OF COLORADO (US) 2014-08-07 WO claimed
EP-1572728-B1 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF MOUNTAIN VIEW PHARMACEUTICALS (US) 2014-06-25 EP claimed
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2012-05-10 US claimed
US-8129330-B2 Complex of polyoxyethylene glycol with active material MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2012-03-06 US claimed
JP-2006510601-A 2006-03-30 JP claimed
EP-1572728-A2 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF Mountain View Pharmaceuticals, Inc. (US) 2005-09-14 EP claimed
EP-1421175-A4 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS (US) 2004-12-08 EP claimed
EP-1421175-A2 POLYMER STABILIZED PROTEINASES Mountain View Pharmaceuticals, Inc. (US) 2004-05-26 EP claimed
WO-2004030617-A2 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2004-04-15 WO claimed
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
US-20030012777-A1 Polymer conjugates of proteinases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2003-01-16 US claimed
WO-2003002716-A2 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2003-01-09 WO claimed
EP-4406536-A2 CYSTATHIONINE BETA-SYNTHASE ENZYME FOR TREATMENT OF HOMOCYSTINURIA The Regents of The University of Colorado, A Body Corporate (US) 2024-07-31 EP disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A FAAH 1966/4885CXCL8 943/4885ALDH1A1 3287/4885
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A FAAH 1966/4885CXCL8 943/4885ALDH1A1 3287/4885
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof CD14, HLA-C, HLA-A FAAH 1966/4885CXCL8 943/4885ALDH1A1 3287/4885
US-20030012777-A1 Polymer conjugates of proteinases PRNP, PRSS3, PRSS1 FAAH 3421/4885CXCL8 3361/4885ALDH1A1 2442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.