SCHEMBL5724314

SCHEMBL5724314

CC(C)(C)[Si](C)(C)OCc1csc(N2CC(O)C2)n1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 4/20 0.34
LMNA P02545 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
OGA O60502 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15349297 0.85 F2RL3 (0.41) F2RL3LMNAHRH3
SCHEMBL5724298 0.83 HRH3 (0.31) HRH3
SCHEMBL5723956 0.82 HRH3 (0.33) F2RL3HRH3
SCHEMBL15349279 0.80 LMNA (0.56) LMNAMAPT
SCHEMBL5724279 0.75 HRH3 (0.43) HRH3OGAMAPT
SCHEMBL5723999 0.75 OGA (0.35) LMNAOGAMAPT
SCHEMBL5724487 0.74 OGA (0.38) HRH3OGAMAPT
SCHEMBL5724490 0.74 OGA (0.35) LMNAOGAMAPT
SCHEMBL5723814 0.73 OGA (0.39) HRH3OGA
SCHEMBL5723810 0.73 OGA (0.39) HRH3OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1289498-C 1-methylcarbapenem derivatives SANKYO CO (JP) 2006-12-13 CN disclosed
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
CN-1486317-A 1-methylcarbapenem derivatives ������������ʽ���� 2004-03-31 CN disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD F2RL3 3892/4885LMNA 3159/4885HRH3 3678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.