Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980246 | 1.00 | HTR1A (0.32) | HTR1A | |
| SCHEMBL7983339 | 0.81 | NPC1 (0.34) | — | |
| Bromide SCHEMBL5725879 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL2439715 | 0.67 | — | — | |
| SCHEMBL5725809 | 0.66 | DHODH (0.35) | — | |
| SCHEMBL27361170 | 0.65 | KMT2A (0.33) | HTR1A | |
| SCHEMBL7978641 | 0.63 | MEN1 (0.32) | — | |
| SCHEMBL27496291 | 0.61 | CA1 (0.36) | HTR1A | |
| SCHEMBL361398 | 0.59 | HTR1A (0.56) | HTR1A | |
| SCHEMBL6422888 | 0.56 | KMT2A (0.31) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812318-B1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6174909-B1 | FOR TREATING ANALGESIA, PSYCHOSIS, CONVULSIONS, EPILEPSY, ANXIETY, MUSCULAR AND MOVEMENT DISORDERS, SPASTIC DISORDERS OR SYMPTOMS OF HUNTINGTON'S OR PARKINSONS DISEASE | H. LUNDBECK A/S (DK) | 2001-01-16 | — | — | US | disclosed |
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |