Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724892 | 0.93 | HTR2A (0.36) | SOS1ALDH1A1LMNAMAPK1SCD5 | |
| Bromide SCHEMBL5725879 | 0.87 | LMNA (0.36) | ALDH1A1LMNAMAPK1SCD5DHODH | |
| SCHEMBL5726290 | 0.84 | SCN5A (0.38) | ALDH1A1EPHX2KMT2A | |
| SCHEMBL7977242 | 0.81 | SOS1 (0.37) | SOS1ALDH1A1MPOHTR2AHRH1 | |
| SCHEMBL5726307 | 0.81 | GRIN2B (0.44) | ALDH1A1EPHX2NPC1GAARAB9A | |
| SCHEMBL5724558 | 0.81 | GRIN2B (0.44) | ALDH1A1EPHX2NPC1GAARAB9A | |
| SCHEMBL5725809 | 0.80 | DHODH (0.35) | ALDH1A1LMNAMAPK1SCD5DHODH | |
| SCHEMBL5725812 | 0.80 | DHODH (0.35) | ALDH1A1LMNAMAPK1SCD5DHODH | |
| SCHEMBL7983339 | 0.80 | NPC1 (0.34) | NPC1GAARAB9ASMN1; SMN2 | |
| Bromide SCHEMBL5726756 | 0.80 | LMNA (0.44) | ALDH1A1LMNASCD5DHODHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812318-B1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |