Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095406 | 1.00 | LMNA (0.48) | LMNAAKT1TSHRTAAR1PTPN1 | |
| SCHEMBL12000456 | 0.79 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL9740200 | 0.78 | MAOB (0.45) | TSHRPOLBHTTMAPT | |
| SCHEMBL638641 | 0.78 | MAOB (0.45) | TSHRPOLBHTTMAPT | |
| SCHEMBL5725152 | 0.78 | TAAR1 (0.50) | LMNATSHRTAAR1CYP3A4MAPT | |
| SCHEMBL3142790 | 0.76 | LMNA (0.63) | LMNAAKT1TSHRTAAR1PTPN1 | |
| SCHEMBL60686 | 0.76 | FASN (0.45) | TAAR1CYP3A4MAPT | |
| SCHEMBL30226689 | 0.75 | LMNA (0.48) | LMNATSHRTAAR1ACHE | |
| SCHEMBL28660105 | 0.74 | PSEN1 (0.41) | LMNAAKT1TSHRMAPTCYP2C19 | |
| SCHEMBL1930872 | 0.74 | PSEN1 (0.41) | LMNAAKT1TSHRMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376413-B1 | Succinic anhydrides from epoxides | CORNELL UNIVERSITY (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376413-B1 | Succinic anhydrides from epoxides | CORNELL UNIVERSITY (US) | 2016-06-28 | — | — | US | disclosed |
| US-8921581-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921581-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8481756-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481756-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-07-09 | — | — | US | disclosed |