Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.39 |
| ▸ | LOX | P28300 | 6/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490171 | 0.86 | CYP4F2 (0.41) | ALDH1A1LOXL2LOXCYP4F2CYP4A11 | |
| SCHEMBL27585619 | 0.84 | RECQL (0.42) | RECQLALDH1A1LOXL2LOXCYP4F2 | |
| SCHEMBL6204914 | 0.79 | RECQL (0.46) | RECQLLOXL2LOXCYP4F2CYP4A11 | |
| SCHEMBL5725243 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL29127669 | 0.77 | RAB9A (0.47) | ALDH1A1GAA | |
| SCHEMBL10672147 | 0.77 | RECQL (0.41) | RECQLALDH1A1LOXL2LOXCYP4F2 | |
| SCHEMBL28484384 | 0.75 | ALDH1A1 (0.35) | ALDH1A1CYP4F2CYP4A11PGRGAA | |
| SCHEMBL29841247 | 0.74 | LOXL2 (0.67) | RECQLLOXL2LOXGRM2 | |
| SCHEMBL17752 | 0.74 | LOXL2 (0.67) | RECQLLOXL2LOXGRM2 | |
| SCHEMBL2940362 | 0.73 | RECQL (0.50) | RECQLLOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902404-A | Therapeutic compounds and compositions | 艾克赛特赫拉制药有限责任公司 | 2020-11-06 | — | — | CN | disclosed |