Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725481 | 0.79 | ALDH1A1 (0.46) | GRM1KDM4EALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL5726467 | 0.78 | CA1 (0.49) | GRM1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11723022 | 0.74 | MEN1 (0.48) | GRM1KDM4EALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL2916208 | 0.73 | GRM1 (0.52) | GRM1SMN1; SMN2CYP1A2CYP2C9LMNA | |
| SCHEMBL5418153 | 0.72 | LMNA (0.42) | GRM1SMN1; SMN2ESR1ESR2CYP1A2 | |
| SCHEMBL3374587 | 0.72 | ANPEP (0.46) | GRM1SMN1; SMN2ESR1ESR2LMNA | |
| SCHEMBL5429466 | 0.72 | GRM1 (0.51) | GRM1SMN1; SMN2CYP1A2CYP2C9LMNA | |
| SCHEMBL5724888 | 0.72 | ESR1 (0.36) | GRM1SMN1; SMN2ESR1ESR2MEN1 | |
| SCHEMBL2918059 | 0.71 | LMNA (0.40) | GRM1SMN1; SMN2ESR1ESR2MEN1 | |
| SCHEMBL2916938 | 0.70 | LMNA (0.40) | GRM1SMN1; SMN2ESR1ESR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188745-B1 | HETEROCYCLIC DICARBOXYLIC ACID DIAMIDE DERIVATIVES, AGRICULTURAL/HORTICULTURAL INSECTICIDES AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-6747041-B1 | PROTECT USEFUL CROPS AGAINST INSECT PESTS, SUCH AS MOTHS, FLIES, WORMS, NEMATODES, CATERPILLARS | NIHON NOHYAKU CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1188745-A1 | HETEROCYCLIC DICARBOXYLIC ACID DIAMIDE DERIVATIVES, AGRICULTURAL/HORTICULTURAL INSECTICIDES AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |