Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.49 |
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725885 | 0.80 | CA1 (0.54) | CA1CA2ALDH1A1HTTHSD17B10 | |
| SCHEMBL5725522 | 0.78 | GRM1 (0.42) | ALDH1A1HSD17B10CYP2C9GRM1SMN1; SMN2 | |
| SCHEMBL2916208 | 0.77 | GRM1 (0.52) | CYP2C9GRM1SMN1; SMN2GRM4 | |
| SCHEMBL11723801 | 0.76 | L3MBTL1 (0.70) | CA1CA2ALDH1A1HTTHSD17B10 | |
| SCHEMBL3374587 | 0.76 | ANPEP (0.46) | GRM1SMN1; SMN2GRM4 | |
| SCHEMBL5418153 | 0.76 | LMNA (0.42) | CYP2C9GRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5429466 | 0.76 | GRM1 (0.51) | CYP2C9GRM1SMN1; SMN2GRM4 | |
| SCHEMBL5724888 | 0.75 | ESR1 (0.36) | GRM1SMN1; SMN2MEN1KMT2AGRM4 | |
| SCHEMBL2918059 | 0.74 | LMNA (0.40) | GRM1SMN1; SMN2MEN1KMT2AGRM4 | |
| SCHEMBL2916938 | 0.73 | LMNA (0.40) | CA2GRM1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188745-B1 | HETEROCYCLIC DICARBOXYLIC ACID DIAMIDE DERIVATIVES, AGRICULTURAL/HORTICULTURAL INSECTICIDES AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-6747041-B1 | PROTECT USEFUL CROPS AGAINST INSECT PESTS, SUCH AS MOTHS, FLIES, WORMS, NEMATODES, CATERPILLARS | NIHON NOHYAKU CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1188745-A1 | HETEROCYCLIC DICARBOXYLIC ACID DIAMIDE DERIVATIVES, AGRICULTURAL/HORTICULTURAL INSECTICIDES AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |