Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727655 | 0.96 | NR1H2 (0.37) | PTGESNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL5726494 | 0.92 | HSD17B2 (0.40) | NR1H2NR1H3KMT2AHSD17B2MAPT | |
| SCHEMBL5727601 | 0.92 | PTGES (0.39) | PTGESNR1H2NR1H3GAAHSD17B2 | |
| SCHEMBL5728616 | 0.90 | KDM4E (0.43) | PTGESNR1H2NR1H3RXFP1MAPT | |
| SCHEMBL5728382 | 0.90 | NR1H2 (0.33) | PTGESNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL5726599 | 0.87 | MEN1 (0.37) | MEN1KMT2ARXFP1TP53MAPT | |
| SCHEMBL5728721 | 0.87 | TDP2 (0.40) | PTGESNR1H2NR1H3MAPTMAPK1 | |
| SCHEMBL8942725 | 0.85 | NR1H2 (0.49) | PTGESNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL5726912 | 0.84 | NR1H2 (0.36) | PTGESNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL5727482 | 0.83 | TDP2 (0.32) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425278-B1 | INSECTICIDAL 3-(2,6-DISUBSTITUTED PHENYL)-5- 4- OR 5-ARYLTHIEN-2- OR -3-YL|-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| US-7056940-B2 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC (US) | 2006-06-06 | — | — | US | disclosed |
| US-6949576-B2 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040171661-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | HEGDE VIDYADHAR BABU (US) | 2004-09-02 | — | — | US | disclosed |
| US-6770665-B2 | TRIAZOLE COMPOUNDS HAVING A 2,6-DISUBSTITUTED-PHENYL GROUP IN THE 3-POSITION, ARYLTHIEN-2- OR -3-YL IN THE 5-POSITION AND AN ALKYL GROUP IN THE 1-POSITION ARE EFFECTIVE IN CONTROLLING LEPIDOPTERA, COLEOPTERA, MITES AND OTHER SUCKING PESTS. | DOW AGROSCIENCES LLC | 2004-08-03 | — | — | US | disclosed |
| US-20040072887-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | HEGDE VIDYADHAR BABU (US) | 2004-04-15 | — | — | US | disclosed |
| US-20030134748-A1 | Insecticial 3-(2,6-disubstituted phenyl)-5-[4- or 5-arylthien-2- or -3-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171661-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PTGES 2008/4885NR1H2 4351/4885NR1H3 4270/4885 |
| US-20040072887-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PTGES 2070/4885NR1H2 4371/4885NR1H3 4250/4885 |
| US-20030134748-A1 | Insecticial 3-(2,6-disubstituted phenyl)-5-[4- or 5-arylthien-2- or -3-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PTGES 2084/4885NR1H2 4335/4885NR1H3 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.