Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072255 | 0.92 | MEN1 (0.37) | OPRD1MGLLMEN1GLATSHR | |
| SCHEMBL4684882 | 0.90 | MEN1 (0.36) | OPRD1MGLLMEN1GLATSHR | |
| SCHEMBL5727486 | 0.88 | MGLL (0.37) | OPRD1MGLLMEN1GLATSHR | |
| SCHEMBL5727699 | 0.86 | CNR1 (0.38) | MGLLMEN1GLATSHRKMT2A | |
| SCHEMBL5727680 | 0.85 | MGLL (0.41) | MGLLMEN1GLATSHRKMT2A | |
| SCHEMBL4787427 | 0.84 | CNR1 (0.36) | MGLLMEN1GLATSHRKMT2A | |
| SCHEMBL5727485 | 0.83 | TSHR (0.37) | OPRD1MGLLMEN1GLATSHR | |
| SCHEMBL4080122 | 0.82 | CNR1 (0.40) | MGLLMEN1GLATSHRKMT2A | |
| SCHEMBL5727631 | 0.82 | MEN1 (0.37) | SLC6A9MGLLMEN1GLATSHR | |
| SCHEMBL3481436 | 0.81 | NOTUM (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636181-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | Merck & Co., Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005000809-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2005-01-06 | — | — | WO | claimed |