Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903821 | 1.00 | NR1I2 (0.33) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL3907629 | 0.94 | NR1I2 (0.33) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL3899480 | 0.91 | GPR139 (0.34) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL1890458 | 0.91 | CCKBR (0.33) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL3900169 | 0.91 | CCR2 (0.37) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL3902491 | 0.90 | KCNA5 (0.38) | — | |
| SCHEMBL3899485 | 0.89 | PDE2A (0.40) | GPR139 | |
| SCHEMBL3901585 | 0.87 | KCNA5 (0.38) | NR1I2SCN1ASCN1BSCN5ASCN8A | |
| SCHEMBL3903757 | 0.87 | L3MBTL1 (0.38) | CCKARCCKBR | |
| SCHEMBL3902499 | 0.87 | PDPK1 (0.32) | SLC22A2GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675837-A2 | BENZO [1,2,5] THIADIAZOLE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005012275-A2 | BENZO [1, 2, 5] THIADIAZOLE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-10 | — | — | WO | disclosed |