Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5729545 | 0.77 | — | — | |
| Acetic Acid SCHEMBL27759376 | 0.75 | FFAR3 (0.44) | — | |
| Carbamic Acid SCHEMBL27422028 | 0.75 | ACHE (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL4345243 | 0.73 | CES1 (0.48) | CES1 | |
| Trifluoroacetic Acid SCHEMBL8677566 | 0.73 | — | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.72 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.72 | ALDH1A1 (0.44) | CES1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.72 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.72 | ALDH1A1 (0.44) | CES1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL474 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137508-A | 5-HT2CReceptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
| WO-2005042491-A1 | BENZAZEPINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT2C RECEPTOR ASSOCIATED DISEASES | ARENA PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |