Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 8/20 | 0.34 |
| ▸ | RELA | Q04206 | 8/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 5/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092141 | 0.81 | L3MBTL1 (0.35) | NFKB1NFKB2RELAGRM2 | |
| SCHEMBL7850920 | 0.79 | ALDH1A1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL27605201 | 0.75 | DRD2 (0.33) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL7110632 | 0.72 | CHRM3 (0.40) | DRD2DRD3 | |
| SCHEMBL7110625 | 0.72 | CHRM3 (0.40) | DRD2DRD3 | |
| SCHEMBL6749348 | 0.72 | NFKB1 (0.62) | NFKB1NFKB2RELA | |
| SCHEMBL14046826 | 0.72 | L3MBTL1 (0.36) | NFKB1NFKB2RELA | |
| SCHEMBL6636676 | 0.71 | DRD2 (0.42) | DRD2DRD4DRD3 | |
| SCHEMBL14046830 | 0.71 | L3MBTL1 (0.38) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL8902349 | 0.71 | DRD2 (0.42) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202243-A | Thermosetting resin composition, cured film, substrate, and electronic component | 捷恩智株式会社 | 2025-06-24 | — | — | CN | disclosed |
| CN-100369916-C | 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity | WYETH CORP (US) | 2008-02-20 | — | — | CN | disclosed |
| EP-1409490-B1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA A|NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | WYETH CORP (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1421086-B1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA a|NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | WYETH CORP (US) | 2006-08-30 | — | — | EP | disclosed |
| CN-1555377-A | 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity | — | 2004-12-15 | — | — | CN | disclosed |
| EP-1421086-A1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA a]NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | Wyeth (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1409490-A1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA A]NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | Wyeth (US) | 2004-04-21 | — | — | EP | disclosed |
| US-6541501-B2 | Dopamine autoreceptor agonists | WYETH | 2003-04-01 | — | — | US | disclosed |
| US-6541502-B1 | Treatment of disorders associated with dopamine dysregulation such as schizophrenia | WYETH | 2003-04-01 | — | — | US | disclosed |
| US-20030037701-A1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA[A]-NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | WYETH | 2003-02-27 | — | — | US | disclosed |
| WO-2003008420-A1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA[A]NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | WYETH (US) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003008419-A1 | 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA[a]NAPHTHALENYL DERIVATIVES WITH ANTIPSYCHOTIC ACTIVITY | WYETH (US) | 2003-01-30 | — | — | WO | disclosed |