Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GFER | P55789 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730840 | 0.82 | KMT2A (0.60) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5731591 | 0.77 | KMT2A (0.64) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5730153 | 0.75 | GFER (0.62) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL10777223 | 0.75 | HTR1B (0.57) | CYP1A2CYP2D6LMNAPTGS2TSHR | |
| SCHEMBL5731407 | 0.71 | MAPT (0.66) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3163430 | 0.70 | MAPT (0.65) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3180041 | 0.69 | KMT2A (0.63) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3176463 | 0.69 | MAPT (0.98) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5732396 | 0.69 | KMT2A (0.57) | KMT2AGFERMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL10614759 | 0.69 | PTGS2 (0.61) | KMT2AMAPTMEN1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
| WO-2021257697-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-23 | — | — | WO | disclosed |
| EP-1651613-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | Aventis Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014555-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | BECN1, SQSTM1, ATG7 | KMT2A 3871/4885GFER 4284/4885MAPT 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.