Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047233 | 0.91 | CHRND (0.44) | — | |
| SCHEMBL3936972 | 0.90 | REN (0.47) | RENNAAA | |
| SCHEMBL4040963 | 0.90 | REN (0.47) | RENNAAA | |
| SCHEMBL4038910 | 0.83 | CHRND (0.48) | REN | |
| SCHEMBL4037775 | 0.77 | REN (0.49) | REN | |
| SCHEMBL4045730 | 0.77 | MMP8 (0.45) | RENNAAA | |
| SCHEMBL4039170 | 0.75 | HPGD (0.41) | — | |
| SCHEMBL4043492 | 0.75 | VNN1 (0.39) | REN | |
| SCHEMBL4044987 | 0.73 | MMP8 (0.51) | — | |
| SCHEMBL5730466 | 0.68 | REN (0.70) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651592-A2 | NOVEL DIBENZO[B,F]OXEPINE-10-CARBOXAMIDES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014517-A2 | NOVEL DIBENZO[B,F]OXEPINE-10-CARBOXAMIDES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |