Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.44 |
| ▸ | CHRNG | P07510 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730463 | 0.91 | REN (0.41) | — | |
| SCHEMBL4040963 | 0.90 | REN (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3936972 | 0.90 | REN (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4038910 | 0.87 | CHRND (0.48) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL4037775 | 0.79 | REN (0.49) | — | |
| SCHEMBL4045730 | 0.77 | MMP8 (0.45) | — | |
| SCHEMBL4039170 | 0.75 | HPGD (0.41) | — | |
| SCHEMBL4043492 | 0.75 | VNN1 (0.39) | — | |
| SCHEMBL4044987 | 0.73 | MMP8 (0.51) | — | |
| SCHEMBL4041195 | 0.72 | MMP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463728-B1 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | disclosed |