Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874023 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1PLCG1ESR1TAAR1 | |
| SCHEMBL30631792 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1PLCG1ESR1TAAR1 | |
| Hydrochloric Acid SCHEMBL28376010 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPK1PLCG1ESR1TAAR1 | |
| SCHEMBL28036157 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPK1ESR1TAAR1CA1 | |
| SCHEMBL437240 | 0.78 | APOBEC3G (0.33) | ALDH1A1GAA | |
| SCHEMBL80035 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPK1PLCG1ESR1TAAR1 | |
| SCHEMBL1168198 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1 | |
| SCHEMBL30282355 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1 | |
| SCHEMBL1330156 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1 | |
| SCHEMBL20186660 | 0.74 | ESR1 (0.35) | ALDH1A1MAPK1ESR1TAAR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724860-B | Alkynyl Au (I) organic complex containing pyrazinoimidazole carbene ligand, and preparation method and application thereof | 中国科学院理化技术研究所 | 2024-12-13 | — | — | CN | disclosed |
| CN-115724860-A | Alkynyl Au (I) organic complex containing pyrazinoimidazole carbene ligand as well as preparation method and application thereof | 中国科学院理化技术研究所 | 2023-03-03 | — | — | CN | disclosed |
| CN-102060779-B | Method for preparing 2-aminobenzimidazole derivative | UNIV TSINGHUA | 2012-07-25 | — | — | CN | disclosed |
| CN-102060779-A | Method for preparing 2-aminobenzimidazole derivative | UNIV TSINGHUA | 2011-05-18 | — | — | CN | disclosed |
| EP-1735293-A2 | SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20050239790-A1 | Substituted hydroxyethylamine aspartyl protease inhibitors | ELAN PHARMACEUTICALS, INC. | 2005-10-27 | — | — | US | disclosed |
| WO-2005087752-A2 | SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-6716352-B1 | TRANSFERRING ACIDIC STRIPPING SOLUTION ACROSS SELECTIVELY PERMEABLE MEMBRANE | MEMBRANE EXTRACTION TECHNOLOGY LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| EP-1210297-A1 | METHOD FOR REMOVING AND RECOVERING AROMATIC AMINES BY USING A NON-POROUS MEMBRANE | Membrane extraction Technology Ltd. (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001009042-A1 | METHOD FOR REMOVING AND RECOVERING AROMATIC AMINES BY USING A NON-POROUS MEMBRANE | MEMBRANE EXTRACTION TECHNOLOGY LIMITED (GB) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239790-A1 | Substituted hydroxyethylamine aspartyl protease inhibitors | DNPEP, MME, ANPEP | ALDH1A1 1971/4885MAPK1 2993/4885PLCG1 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.