Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 10/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 10/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115083 | 0.91 | NQO1 (0.55) | ESR1ESR2NQO1CSNK2A2CSNK2B | |
| SCHEMBL5118711 | 0.89 | CSNK2A2 (0.47) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5120320 | 0.78 | ESR2 (0.43) | ESR2NQO1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5125176 | 0.71 | MAOB (0.56) | NQO1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5115329 | 0.71 | MAOB (0.44) | ESR1ESR2NQO1CSNK2A2CSNK2B | |
| SCHEMBL5117787 | 0.70 | ESR2 (0.40) | ESR1ESR2NQO1CSNK2A2CSNK2B | |
| SCHEMBL5126114 | 0.69 | MAPT (0.38) | ESR1ESR2NQO1 | |
| SCHEMBL5115327 | 0.69 | FAAH (0.37) | ESR2 | |
| SCHEMBL5111278 | 0.68 | ALDH1A1 (0.48) | — | |
| SCHEMBL5118825 | 0.68 | NQO1 (0.52) | ESR1ESR2NQO1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648902-A1 | SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-04-26 | — | — | EP | claimed |
| WO-2005010007-A1 | SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION | PLIVA- ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-02-03 | — | — | WO | claimed |