Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732075 | 0.89 | GRIA2 (0.40) | GCGRALDH1A1MAPK14GRIA2GRIA4 | |
| SCHEMBL5731277 | 0.85 | MAPT (0.41) | ALDH1A1 | |
| SCHEMBL5730843 | 0.74 | GRIA2 (0.43) | ALDH1A1MAPK14RIPK3GRIA2GRIA4 | |
| SCHEMBL5731592 | 0.65 | HMGCR (0.43) | ALDH1A1GRIA2GRIA4HMGCR | |
| SCHEMBL5731885 | 0.65 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL5731420 | 0.62 | HMGCR (0.45) | ALDH1A1HMGCR | |
| SCHEMBL29720848 | 0.62 | MMP1 (0.35) | ALDH1A1MAPK14GRIA2GRIA4HMGCR | |
| SCHEMBL5731467 | 0.61 | HMGCR (0.52) | HMGCR | |
| SCHEMBL5731954 | 0.61 | ALDH1A1 (0.46) | GCGRALDH1A1MAPK14 | |
| SCHEMBL557586 | 0.61 | MAPK14 (0.51) | ALDH1A1MAPK14HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050154042-A1 | N-alkyl pyrroles as HMG-CoA reductase inhibitors | WARNER-LAMBERT COMPANY | 2005-07-14 | — | — | US | disclosed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154042-A1 | N-alkyl pyrroles as HMG-CoA reductase inhibitors | HMGCR, DHCR7, CYP11A1 | GCGR 1255/4885ALDH1A1 1452/4885MAPK14 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.