Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689833 | 0.82 | HCAR2 (0.41) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL6898204 | 0.81 | HCAR2 (0.34) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL151395 | 0.80 | HCAR2 (0.43) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL3690825 | 0.80 | ALOX15 (0.35) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL2173060 | 0.80 | ALOX15 (0.35) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL7425210 | 0.77 | HCAR2 (0.46) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL11119674 | 0.77 | HTR7 (0.36) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL1437210 | 0.74 | TSHR (0.31) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL948656 | 0.74 | HCAR2 (0.49) | ALOX15TSHRKDM4EACMSDTDP1 | |
| SCHEMBL1082482 | 0.73 | HCAR2 (0.50) | ALOX15TSHRKDM4ETDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694638-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058808-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |