Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605574 | 0.85 | PKM (0.31) | HCAR2KDM4ENPSR1PKM | |
| SCHEMBL29388344 | 0.83 | LMNA (0.38) | TSHRNPSR1ALDH1A1PKM | |
| SCHEMBL3690825 | 0.82 | ALOX15 (0.35) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL5732065 | 0.82 | ALOX15 (0.35) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL10590211 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2173060 | 0.82 | ALOX15 (0.35) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL151395 | 0.82 | HCAR2 (0.43) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL7425210 | 0.79 | HCAR2 (0.46) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL6898204 | 0.79 | HCAR2 (0.34) | HCAR2TSHRALOX15KDM4EACMSD | |
| SCHEMBL11119674 | 0.79 | HTR7 (0.36) | HCAR2TSHRALOX15KDM4EACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106750358-B | A kind of imidazole-2-carboxylic acid's nickel complex, preparation method and applications | 河南中医药大学 | 2019-10-15 | — | — | CN | claimed |
| CN-106750359-B | A kind of imidazole-2-carboxylic acid's cobalt complex, preparation method and applications | 河南中医药大学 | 2019-08-23 | — | — | CN | claimed |
| CN-106750359-A | A kind of imidazole-2-carboxylic acid's cobalt complex, preparation method and applications | 河南中医药大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106750358-A | A kind of imidazole-2-carboxylic acid's nickel complex, preparation method and applications | 河南中医药大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106750358-B | A kind of imidazole-2-carboxylic acid's nickel complex, preparation method and applications | 河南中医药大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-106750358-B | A kind of imidazole-2-carboxylic acid's nickel complex, preparation method and applications | 河南中医药大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-106750359-B | A kind of imidazole-2-carboxylic acid's cobalt complex, preparation method and applications | 河南中医药大学 | 2019-08-23 | — | — | CN | disclosed |
| CN-106750359-B | A kind of imidazole-2-carboxylic acid's cobalt complex, preparation method and applications | 河南中医药大学 | 2019-08-23 | — | — | CN | disclosed |
| CN-106750358-A | A kind of imidazole-2-carboxylic acid's nickel complex, preparation method and applications | 河南中医药大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106750359-A | A kind of imidazole-2-carboxylic acid's cobalt complex, preparation method and applications | 河南中医药大学 | 2017-05-31 | — | — | CN | disclosed |
| WO-2015009882-A2 | CYANO DERIVATIVES AND THEIR USES | THE HAMNER INSTITUTES (US) | 2015-01-22 | — | — | WO | disclosed |
| US-7763607-B2 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2010-07-27 | — | — | US | disclosed |
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254862-A1 | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators | CNR1, CNR2, KCNJ11 | HCAR2 290/4885TSHR 2667/4885ALOX15 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.