Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095695 | 0.88 | RECQL (0.66) | RECQLTSHRBRD4CYP1A2ALDH1A1 | |
| SCHEMBL694562 | 0.85 | RECQL (0.46) | RECQLTSHRBRD4CYP1A2HTT | |
| SCHEMBL17044159 | 0.81 | GRIN1 (0.47) | RECQLBRD4CYP1A2ALDH1A1CYP19A1 | |
| SCHEMBL28716990 | 0.80 | RECQL (0.69) | RECQLTSHRBRD4CYP1A2HSD17B10 | |
| SCHEMBL248214 | 0.80 | RECQL (1.00) | RECQLTSHRBRD4CYP1A2ALDH1A1 | |
| SCHEMBL30346162 | 0.80 | RECQL (1.00) | RECQLTSHRBRD4CYP1A2ALDH1A1 | |
| SCHEMBL17044140 | 0.77 | ALDH1A1 (0.44) | RECQLTSHRCYP1A2ALDH1A1HTT | |
| SCHEMBL16617171 | 0.77 | CYP1A2 (0.39) | RECQLTSHRCYP1A2HSD17B10KMO | |
| SCHEMBL188240 | 0.77 | CYP1A2 (0.39) | RECQLTSHRCYP1A2HTTHSD17B10 | |
| SCHEMBL18131298 | 0.74 | RECQL (0.47) | RECQLCYP1A2ALDH1A1KDM4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874353-B | Microbiocidal derivatives | 先正达农作物保护股份公司 | 2024-06-14 | — | — | CN | claimed |
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-01 | — | — | US | claimed |
| CN-113874353-A | Microbicidal derivatives | 先正达农作物保护股份公司 | 2021-12-31 | — | — | CN | claimed |
| WO-2020239856-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-03 | — | — | WO | claimed |
| CN-113874353-B | Microbiocidal derivatives | 先正达农作物保护股份公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-3752492-B1 | FUNGICIDAL OXADIAZOLES | BAYER AG (DE) | 2022-12-21 | — | — | EP | disclosed |
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-01 | — | — | US | disclosed |
| CN-113874353-A | Microbicidal derivatives | 先正达农作物保护股份公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20210009541-A1 | FUNGICIDAL OXADIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-01-14 | — | — | US | disclosed |
| WO-2020239856-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-03 | — | — | WO | disclosed |
| EP-1778639-B1 | ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN | ALBANY MOLECULAR RES INC (US) | 2015-09-02 | — | — | EP | disclosed |
| US-20060063766-A1 | Use of aryl- and heteroaryl-substituted tetrahydroisoquinolines to block reuptake of norepinephrine, dopamine, and serotonin | ALBANY MOLECULAR RESEARCH, INC. | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063766-A1 | Use of aryl- and heteroaryl-substituted tetrahydroisoquinolines to block reuptake of norepinephrine, dopamine, and serotonin | SLC6A3, SLC6A4, SLC6A2 | RECQL 443/4885TSHR 297/4885BRD4 148/4885 |
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | MPO, MSR1, PRF1 | RECQL 3624/4885TSHR 2631/4885BRD4 3990/4885 |
| US-20210009541-A1 | FUNGICIDAL OXADIAZOLES | OXA1L, CYP51A1, CYP4X1 | RECQL 3914/4885TSHR 3891/4885BRD4 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.