Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 10/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705788 | 0.88 | KDM4E (0.56) | ALDH1A1HPGDMAPK1MEN1NPC1 | |
| SCHEMBL694852 | 0.88 | ALDH1A1 (0.56) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28928759 | 0.87 | ESR1 (0.49) | ALDH1A1HPGDMAPK1MEN1NPC1 | |
| SCHEMBL10222539 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10MAPK1MMP13 | |
| SCHEMBL3612395 | 0.86 | MAPT (0.57) | ALDH1A1HPGDHSD17B10MAPK1MEN1 | |
| SCHEMBL1173463 | 0.86 | PRKCZ (0.54) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL204475 | 0.85 | L3MBTL1 (0.57) | ALDH1A1HPGDCDK5CDK5R1MAPK1 | |
| SCHEMBL4408696 | 0.85 | KDM4E (0.59) | ALDH1A1HPGDMEN1NPC1MAPT | |
| SCHEMBL18425631 | 0.85 | RAB9A (0.57) | ALDH1A1MAPK1MEN1NPC1MAPT | |
| SCHEMBL17396331 | 0.82 | GAA (0.56) | ALDH1A1HPGDMAPK1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |