Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733324 | 0.86 | PGK1 (0.34) | LMNASMN1; SMN2RAB9ACYP1A2CYP2C9 | |
| SCHEMBL5733237 | 0.75 | PTK2 (0.49) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL5733664 | 0.75 | KDR (0.31) | — | |
| SCHEMBL5735229 | 0.75 | CYP2A6 (0.31) | CYP2C9CYP2C19 | |
| SCHEMBL3208582 | 0.73 | GABRP (0.40) | LMNASMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL1182532 | 0.73 | MAPK8 (0.42) | L3MBTL1MAPK8MAPK9 | |
| SCHEMBL6772300 | 0.72 | — | — | |
| SCHEMBL6984523 | 0.71 | L3MBTL1 (0.42) | LMNASMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL5733210 | 0.70 | KDR (0.30) | — | |
| SCHEMBL7091354 | 0.68 | L3MBTL1 (0.40) | SMN1; SMN2HPGDRAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| CN-1152029-C | Quinolonecarboxylic acid derivatives or salts thereof | ��ɽ��ѧ��ҵ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| CN-1299356-A | Quinolonecarboxylic acid derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |