Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.70 |
| ▸ | CHUK | O15111 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28240691 | 0.84 | GPR55 (0.65) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL7961737 | 0.80 | GPR55 (0.59) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL5736756 | 0.78 | CASP3 (1.00) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL17595755 | 0.78 | NOTUM (1.00) | GPR55NOTUMMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1957044 | 0.75 | MAPT (0.45) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL28653242 | 0.75 | SMN1; SMN2 (1.00) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL28642673 | 0.75 | RAB9A (1.00) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL7399348 | 0.75 | GPR55 (0.71) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL1473020 | 0.74 | NR1H4 (1.00) | GPR55CHUKCASP3TXNRD1SENP8 | |
| SCHEMBL117091 | 0.74 | PDCD1 (0.65) | ALDH1A1MAPK1TSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934288-B1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-0934288-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017652-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-04-30 | — | — | WO | disclosed |