Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29233063 | 0.90 | TSHR (0.50) | CYP2C9LMNAHKDC1TSHRHDAC4 | |
| SCHEMBL19433091 | 0.84 | HKDC1 (0.49) | CYP2C9LMNAHKDC1TSHRHDAC4 | |
| SCHEMBL16528760 | 0.84 | AOC3 (0.43) | LMNAHKDC1TSHRHDAC4HDAC2 | |
| SCHEMBL9269923 | 0.82 | CYP2C9 (0.45) | CYP2C9LMNAHKDC1TSHRHSD17B10 | |
| SCHEMBL27898104 | 0.82 | EP300 (0.41) | CYP2C9LMNAHKDC1KDM4EPOLB | |
| SCHEMBL27661251 | 0.82 | BCHE (0.61) | CYP2C9LMNAHKDC1TSHRHDAC4 | |
| SCHEMBL1238318 | 0.81 | TSHR (0.63) | CYP2C9LMNAHKDC1TSHRHDAC4 | |
| SCHEMBL16528244 | 0.80 | SIGMAR1 (0.46) | ALDH1A1HTR2AHRH1 | |
| SCHEMBL28263630 | 0.80 | BCHE (0.48) | CYP2C9LMNATSHRHDAC4HDAC2 | |
| SCHEMBL31545182 | 0.79 | TRPA1 (0.53) | CYP2C9TSHRHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | claimed |
| CN-108472220-B | Reducing the perception of skin stinging | 西姆莱斯股份公司 | 2022-06-17 | — | — | CN | claimed |
| EP-3373895-B1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| CN-104414869-B | A kind of skin and/or hair whitening mixture | 西姆莱斯股份公司 | 2019-09-03 | — | — | CN | claimed |
| EP-3373895-A1 | REDUCTION OF STINGING SENSATION ON SKIN | Symrise AG (DE) | 2018-09-19 | — | — | EP | claimed |
| CN-108472220-A | Reduce skin irritation impression | 西姆莱斯股份公司 | 2018-08-31 | — | — | CN | claimed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | claimed |
| CN-104414869-A | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG | 2015-03-18 | — | — | CN | claimed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | claimed |
| EP-1879457-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-01-23 | — | — | EP | claimed |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | CIBA SPECIALTY CHEMICALS CORP. | 2007-10-04 | — | — | US | claimed |
| EP-1755381-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-02-28 | — | — | EP | claimed |
| WO-2006120135-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-11-16 | — | — | WO | claimed |
| US-20060040847-A1 | Hard surface treating compositions | RECKITT BENCKISER INC. | 2006-02-23 | — | — | US | claimed |
| WO-2005107456-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-17 | — | — | WO | claimed |
| EP-1537201-A1 | HARD SURFACE TREATING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-06-08 | — | — | EP | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| WO-2004024861-A1 | HARD SURFACE TREATING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-03-25 | — | — | WO | claimed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | STING1, TYR, CUTA | CYP2C9 4350/4885LMNA 3940/4885HKDC1 4412/4885 |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | TYR, AHR, CYP1B1 | CYP2C9 178/4885LMNA 325/4885HKDC1 2222/4885 |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | SIK2, SIK3, SIK1 | CYP2C9 2461/4885LMNA 4300/4885HKDC1 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.