SCHEMBL573718

SCHEMBL573718

CCc1cccc(Cl)c1O

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.70
GABRB2 P47870 5/20 0.70
HSP90AA1 P07900 1/20 0.53
CA1 P00915 1/20 0.45
ACHE P22303 1/20 0.45
EGFR P00533 2/20 0.44
ERBB2 P04626 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PNMT P11086 1/20 0.41
ALOX12 P18054 1/20 0.41
SHBG P04278 1/20 0.40
ALDH1A1 P00352 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624471 0.90 GABRA1 (0.57) GABRA1GABRB2HSP90AA1CA1ACHE
SCHEMBL23250736 0.85 GABRA1 (0.61) GABRA1GABRB2HSP90AA1EGFRPNMT
SCHEMBL199730 0.83 GABRA1 (1.00) GABRA1GABRB2
SCHEMBL1552241 0.83 HSP90AA1 (0.50) GABRA1GABRB2HSP90AA1CA1ACHE
SCHEMBL9751984 0.81 HSP90AA1 (0.74) GABRA1GABRB2HSP90AA1CA1ACHE
SCHEMBL574233 0.79 ALOX5 (0.53) GABRA1GABRB2HSP90AA1EGFRERBB2
SCHEMBL28094939 0.79 HSP90AA1 (0.47) GABRA1GABRB2HSP90AA1CA1ACHE
SCHEMBL5710254 0.79 HSP90AA1 (0.55) GABRA1GABRB2HSP90AA1CA1ACHE
SCHEMBL24451093 0.79 GABRA1 (0.52) GABRA1GABRB2HSP90AA1
Alcohol SCHEMBL28268569 0.78 GABRA1 (0.90) GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875110-A Polyphenylene ether, polyphenylene ether solution, resin film, prepreg, and metal-clad laminate 旭化成株式会社 2025-04-25 CN claimed
CN-114736367-A Green and safe polyarylether gas-liquid heterogeneous synthesis method 常州中英科技股份有限公司 2022-07-12 CN claimed
CN-114716666-A Polyarylether synthesis method based on gas-liquid heterogeneous phase method and continuous flow microchannel reactor 常州中英科技股份有限公司 2022-07-08 CN claimed
CN-108641077-B Synthetic method of polyphenyl ether 广东省石油与精细化工研究院 2020-07-28 CN claimed
CN-108641077-A A kind of synthetic method of polyphenylene oxide 广东省石油与精细化工研究院 2018-10-12 CN claimed
US-20140135297-A1 AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2014-05-15 US claimed
WO-2012170841-A1 AN AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2012-12-13 WO claimed
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
EP-1549731-B1 CLEANING AND DISINFECTING COMPOSITION RECKITT BENCKISER INC (US) 2008-12-17 EP claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4282899-B1 POLYPHENYLENE ETHER, PRODUCTION METHOD, THERMOSETTING COMPOSITION, PREPREG, AND LAMINATE THEREOF ASAHI CHEMICAL IND (JP) 2025-07-16 EP disclosed
US-4692555-A Preparation of diphenolics ETHYL CORPORATION (US) 1987-09-08 US disclosed
US-4558119-A WITH MANGANESE COMPOUND, N-ALKYLALKANOLAMINE, AND A BASIC COMPOUNDCATALYTIC MIXTURE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
EP-0153074-A2 Process for producing polyphenylene oxides MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-08-28 EP disclosed
EP-0132608-A1 Process for the polymerization of a 2,6-disubstituted phenol Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA GABRA1 3441/4885GABRB2 3092/4885HSP90AA1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.